1st Seminar on ‘Nano-Pico Pharmaceuticals & Invivgensome'


THEME OF THE SEMINAR

  • Concept, opportunities and scope in  Nano-Pico Technologies
  • Role of Nano-Pico Technologies in Pharmaceutical Products.
  • Nano- Pico Structure and their Applications in Pharmaceutical Industries
  • Nano-Pico Technology, Lab Techiques, Diagnosis and Treatment
  • Invivgensome

 In the preliminary session Prof. Giuseppe Tritto stated that nanotechnology is very diverse, ranging from extension of conventional device physics to completely new approaches based upon molecular self assembly, from developing new material with dimension on the nano scale to direct control of matter on atomic scale.  Nano-Pico technology can prove to be a great help in the perspective of medicine and health, transforming life, business, the life science revolution, the link between innovation biotechnology, economy and social welfare.
Prof.Sujoy K Guha described the concept of ‘Nano-Pico Technologies’ and its application in Pharmaceuticals. He coined invivgensome which deals with induced generation of liposomes in different body organs and its in vivo distribution and biological action.

Dr. Anu T Singh, Dabur Research Foundation highlighted nanoparticle based drug delivery systems enabling the drug to reach to the cancer cells. She said that anti-cancer drug Nanoxel based on principles of nanotechnology, which is a creamophor free soluble formulation, and is effective and safe therapy for advanced breast and lung cancer.

Dr. Shivani Sharma from University of California while presenting on Video conferencing said that all living systens contain naturally occurring nanoparticles with unique structural and mechanical characteristics. Especially, human saliva exosomes secreted by normal cells into saliva via exocytes are novel biomarkers showing tumor –antigen enrichment during oral cancer. She showed the structure of  human saliva containg exosomes by using a new ultra sensivtive AFM and confocal microscopy etc.

Dr.R.P.Singh from Amity Institute of Nanotechnology described the Nano-Pico technologies. He differenciated between Nano and Pico technologies by stating that properties of nanoparticles are size dependent and the size of pico is 1000 times smaller than nano (a fraction of an atom); as such, a material does not exist in the size of picometer. This is the size (Pico) of high energy particles like electrons, neutron and proton etc. The responses of bio-physical changes due to interactions within biomolecules in a living system can be measeured in terms of pico frequencies, pico amphere current, pico molar quantities by different pico techniques. Their measurement techniques are now evolved under the field of pico technology. It has applications to measure pico molar quantities of single strand DNA in the evaluation of texotere chemosensitivity arising out of the biophysical interactions of minute quantities of lead, mercury in blood cells of fishes. Pico technology is very relevant to understand the insight of the cellular processes in living cells.

 

He also said that invivgensomes are a new class of liposomal entities assembled within the human body with materials derived from implants and naturally existing biochemicals within the living system.  The designed invivo “manufacturing” of  invivgensome will provide exciting possibilities in therapeutics with lesser toxicology issues compared to in vitro prepared pharmaceuticals. 

During the Session, all the participants unanimously advocated the cautious and judicious use of Nano- Pico technology and substances in Medical Science, taking into consideration the potential adverse effects these substances can cause to human bodies. In most of the Cancer related deaths, it cannot be ascertained whether the patient died of cancer or due to the side effect of the therapy or drugs administered to him. They share their concern about the increased use of carcinogens which are capable of inducing cancer in humans or animals after prolonged or excessive exposure. Ideas were mooted to speed up the research in the new areas of Picotechnology and Nano-Pico Pharmaceuticals like medical applications related to legal issues, toxicity, diagnostics / therapeutics  for the benefit of human beings at large.  Launching of short and longer courses which may familiarize the scientists on regulatory issues related to nanotechnology were suggested.
Other eminent scientists like Prof. Sneh Anand, IIT-Delhi; Prof R.P.Tandon and Prof.P.K.Bhatnager, DU; Dr. R.K.Kotnala, NPL; Dr. Rashi Mathur, INMAS, Delhi exchanged their views on application of Nano-Pico technology.
 Dr. Ashok K.Chauhan, President, Amity Institute of Nanotechnology announced the launching of Amity Foundation for Picotechnologies which would have two website - www.amitypico.com and www.amitypico. orgfor promoting the research in Nano- Picotechnology, which gives a common platform to Scientists and Researchers across the country to synergize their efforts to develop breakthrough ideas and technologies. The Foundation will promote collective intelligence amongst the scientist fraternity across the world. Dr. Ashok K Chauhan would be the Chairperson of the Foundation and Dr. R P Singh- Director, Amity Institute of Nanotechnology would act as Vice- Chairperson of this Foundation.
Amity University Uttar Pradesh is committed undertake research activities in the newly borne scientific disciplines to generate the knowledge for the benefit of humanity.  Join hands  with the Amity Nanotechnology Mission and Amity Foundation for Picotechnologies to fulfill the commitment and achieve the mission.